Molecular Imaging News
February 1, 2006
National Institute of Radiological Sciences Confirms PET Imaging is Useful in Antipsychotic Dosage Selection
National Institute of Radiological Science
The National Institute of Radiological Science (NIRS) announced on January 30 that it has confirmed the utility of positron emission tomography (PET) imaging in determining the optimal dosage of antipsycotics.
Specifically, the NIRS has reevaluated the clinical dosages of two antipsychotics, sulpiride and sultopride, using PET imaging. Currently, the optimal dosages of sulpiride and sultopride are set at 300-600 mg per day.
The reevaluation results show that the optimal dosage of sultpiride is up to 1010–30 mg per day, higher than the currently prescribed amount. Meanwhile, sultopride can exert beneficial effects with only 20–30 mg per day.
Details of these findings will be soon available in the International Journal of Neuropsychopharmacology. Going forward, the NIRS plans to conduct research targeting schizophrenic patients.